Arkady Khoutorsky received his DVM and completed his PhD at the Hebrew University of Jerusalem, Israel, where he investigated mechanisms underlying synaptic plasticity. In 2009, he joined the laboratory of Dr. Nahum Sonenberg, a renowned leader in the field of translation mechanisms, for his postdoctoral training. During his time in Dr. Sonenberg’s lab, he initiated a project aiming to elucidate the role of translational control in sensitization of the pain pathway. His main focuses were on the translation upregulation in different pain conditions and on the development pharmacological and genetic tools for their treatment.
In Sonenberg lab, he led a collaborative study involving behavioural, electrophysiological, biochemical, and genetic approaches, taking advantage of Dr. Sonenberg’s expertise in translational control and Dr. Mogil’s in pain, to study the role of translation control mechanisms in pain. He also characterized new translational control mechanisms involved in synaptic plasticity, learning and memory.
In 2016, he joined the Alan Edwards Centre for Research on Pain at McGill to pursue his independent research focusing on translational control mechanisms in persistent pain.