To federate pain research in Quebec, QPRN has established a research infrastructure model based on a number of consortiums. These consortiums are organized based on specific research proprieties themes identified by our members, partners and people living with chronic pain and are designed to drive innovative research focused on the needs of the Quebec ecosystem.
Objective
The Consortium on Treatment efficacy and safety aims to study all aspects of efficacy and safety, taking into account all the different factors and various contexts of use, with the goal of offering a personalized therapeutic strategy to the majority of people. Over the next few years, efforts will be made to enhance knowledge in the following themes, among others:
- therapeutic profile of laboratory-tested treatments improvement;
- cannabis usage;
- polypharmacy and polytherapy;
- big data analysis.
Members
Directors : Éric Troncy, researcher at Université de Montréal, Mélanie Bérubé, researcher at Université Laval, Laurent Dupuis, patient partner, Claudie Audet and Alexa Coulombe-Levêque (trainee representatives)
Teams group together people from research and clinical backgrounds as well as any other person with expertise relevant to the work.
Progress
- January 19, 2024, Mount Sainte-Anne. Launch of the new consortium and large-group discussion meeting that led to a first team project funding. This project focuses on deprescription of gabapendinoids.
- October 11, 2024, Drummondville. QPRN organized the first in person meeting of this consortium. At this gathering, two projects were selected for funding, focusing respectively on experiential and clinical perspectives of opioid deprescription, and pain management strategies for adults receiving palliative care. Members also emphasized the importance of exploring pharmacoeconomics, nutrition, needs and ways of evaluating treatment effectiveness that differ depending on the life stage.
- December 13, 2024. Launch of a call for projects aiming the research teams and priorities identified at previous meetings. This call led to the selection of two new projects to be funded, focusing respectively on a fundamental approach to understanding the efficacy of analgesics in aging, and a study of the perspective of people living with pain in terms of deprescription approaches.
- October 21, 2025, Québec. Large-group in-person meeting. Add to calendar.
Projects
- Déprescription des gabapentinoïdes : approches et perception des personnes vivant avec de la douleur (Line Guénette, Mélanie Bérubé, Magali Millecamps, Laurent Dupuis, Anne-Marie Pinard, Pascal Tétreault, Éric Troncy, Emily McDonald)
- Déprescription d’opioïdes : Perspectives cliniques et expérientielles sur les besoins en matière d’outils d’accompagnement (Léonie Archambault, Emily McDonald)
- Pain managements strategies in older adults receiving palliative care: a scoping review (Mélanie Bérubé, Lynn Gauthier, Éric Troncy, Diane Tapp, Étienne Belzile, Guillaume Léonard, Line Guénette, Annie Deshaies, Chantal Morency, Norbert Dion, Alexandra Tremblay, Stéphane Pelet)
- Est-ce que les médicaments analgésiques restent efficaces et sécuritaires au cours du vieillissement (Magali Millecamp, Guillaume Léonard)
- Perception des personnes vivant avec de la douleur chronique sur les approches de déprescription (Line Guénette, Anaïs Lacasse, Caroline Sirois, Mélanie Bérubé, Anne-Marie Pinard, Éric Troncy, Laurent Dupuis)
Knowledge Mobilisation
- Annual retreat 2025 : Update on the current progress and presentation of challenges and opportunities encountered
- Semestrial newsletter 2025 : Description of major progress of the consortiums.
Publications
Details to come
Partners
We thank the Canadian Medication Appropriateness and Deprescribing Network for their support and collaboration.
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