Biography
Philippe Séguéla, PhD, is a Full Professor in the Department of Neurology and Neurosurgery at McGill University. Trained in molecular neuroscience in France, Canada, and the United States, his internationally recognized research, funded by CIHR, NSERC, and private organizations, has focused primarily on ion channels that contribute to neuronal hyperexcitability in pain circuits. His laboratory at the Montreal Neurological Institute uses a cutting-edge multidisciplinary approach, including electrophysiology, molecular pharmacology, transgenic mouse models, optogenetics, chemogenetics, calcium imaging, and sensory behavior analysis, to investigate key pathophysiological mechanisms in peripheral and central pain pathways. The goal of Professor Séguéla’s team and collaborators is to understand the molecular and cellular basis of the somatosensory deficits observed in patients suffering from persistent pain and chronic itch, in order to provide a rational foundation for the development of effective non-opioid analgesic therapies.
