Theme 1: Assessing Pain

“Phenotyping pain in animal models and patients”

Leaders: Jeffrey Mogil & Pierre Rainville

Our ability to understand pain and improve its treatment can only be as good as our ability to assess it. Advances in clinical research on pain have been hampered by a lack of systematic assessment of pain sensitivity and responses, as well as the impact of pain and pain relief on physical and mental performance.

The main objectives are to support the development and validation of a comprehensive array of animal and human pain models to establish standardized methodologies for pain measurement and assessment. This includes designing innovative pain testing methods and exporting these methods to pain clinics.
To achieve this we will:

  • Support our existing Network platforms (see below)
  • Facilitate the exchange of information and expertise for the validation of animal and human models to clinical conditions
  • Support pilot studies aimed at designing new models and assessment methods